Peptide Hormones: Facts

Peptides have been a popular choice for performance-enhancing substances over the years. Online products are increasingly including peptides. To treat various medical conditions, a doctor might prescribe peptide hormones like luteinizing or chorionic gonadotrophin.

Important to know that anti-doping regulations apply to athletes. Both releasing and peptide hormones are prohibited by the World Anti-Doping Agency (WADA) Prohibited List Section S2.2. Here are six things athletes and their coaches need to know about releasing hormones and peptide hormonal.

1. What are peptide hormone compounds?

Peptide hormones are hormones that are made up small chains of amino acid. The body can produce many different peptide hormones. They are found in the blood and bind to specific receptors in tissues and organs. They play an important role in reproduction and are produced by the placenta and ovaries.

Corticotrophins and growth hormone are two examples of peptide hormonal. Corticotrophins stimulate the release cortisol, a hormone that helps the body cope with stress. Many tissues of the body are controlled by growth hormone.

2. What are secretagogues?

Secretagogues or releasing factors are substances which stimulate the body to produce and release specific hormones. When it senses LH-releasing hormones in the blood, LH is released by the pituitary gland. There are many substances that can trigger the release hormones like LH, CG, and corticotrophins.

3. Are peptide hormones prohibited?

The WADA Prohibited List Section S2.2 prohibits certain peptide hormones. This includes those with anabolic and strength-enhancing effects. The number of S2 agents grows each year. An S2 agent that has a “similar chemical composition or similar biological effects(s)” could still be banned. allows athletes and support personnel to quickly determine the banned status of individual peptide hormones.

4. What uses can peptide hormones be used in medicine?

LH, CG, and growth hormone are all therapeutically available to treat fertility issues, growth problems, or pituitary deficiencies. Specifically, CG can be used in IVF treatments to assist conception. LH and CG stimulate testosterone production in males.

Many gonadotropin-releasing hormones, such as goserelin and leuprolide (or triptorelin), are used to treat medical conditions such as breast cancer, prostate cancer and endometriosis.

Peptide hormones should only be prescribed by a doctor. They are not approved by the Food and Drug Administration (FDA) for over-the-counter use and should not be included in dietary supplements.

5. What happens if my doctor recommends hormonal treatment?

Before you begin any new treatment or medication, make sure to check the prohibited status. If your medication is prohibited, you might need to apply for a Therapeutic Use Exemption. Athletes should complete the TUE Check form to confirm that they need a TUE.

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